Non-Invasive breakup time: Automatic computerized vs. manual assessment.

Zeri F., Rizzo G. C., Ponzini E., Tavazzi S.
  Mercoledì 13/09   09:00 - 13:30   Aula P1   VI - Fisica applicata, acceleratori e beni culturali   Presentazione
Non-invasive, objective, and automatic assessments of the tear film using keratography are quickly spreading in clinical optometry and ophthalmology. However, few studies have investigated the differences between manual non-invasive breakup time (NIBUT) procedures and the new automatic computer-based ones. This study evaluated the agreement between automatic and manual NIBUT. Eighty-five videos of NIBUT $(6.6 \pm 3.6$ s; range 0--17 s) performed by Sirius+ (CSO, Florence) were selected from the COMiB database. One optometrist recently graduated (Junior) and one optometrist with more than 20 years of experience (Senior) assessed the videos in random order, measuring the NIBUT three times in a row. A significant correlation between automated and manual NIBUT (average of two observers) was found (Spearman Rho = 0.9; $p< 0.001$), but also a significant statistical difference between the two measurements (Wilcoxon test; $p< 0.01$), although clinically negligible (0.3 s). The Senior observer produced a slightly longer average NIBUT (0.9 s), conversely, the Junior one measured a slightly shorter NIBUT compared to the automatic procedure (0.3 s).